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Journal: International Journal of Molecular Sciences
Article Title: The Role of Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK) in Skeletal Muscle Biology and Pathogenesis
doi: 10.3390/ijms25147601
Figure Lengend Snippet: Comparison of BCKDK gene expression between young and old age groups in Male ( A ) and Female ( B ) groups. Skeletal muscle biopsies of the vastus lateralis were obtained from human participants and gene expression was analyzed using Affymetrix (Santa Clara, CA, USA) HG-U133A and HF-U133B high-density oligonucleotide arrays. The data for ( A ) were retrieved from GEO dataset uploaded by Welle et al. GEO ID 1592758) ( n = 7–8) . Identical experimental procedures were used to assess female gene expression. This data from ( B ) were retrieved from GEO dataset uploaded by Welle et al. (GEO ID 3242858) significance determined by GEO2R adjusted * p -value = 0.0148 ( n = 7–8) .
Article Snippet: The skeletal muscle samples were taken from the vastus lateralis, and gene expression analysis was conducted using
Techniques: Comparison, Expressing
Journal: International Journal of Molecular Sciences
Article Title: The Role of Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK) in Skeletal Muscle Biology and Pathogenesis
doi: 10.3390/ijms25147601
Figure Lengend Snippet: Details of the GEO dataset study designs used to examine BCKDK gene expression in different models.
Article Snippet: The skeletal muscle samples were taken from the vastus lateralis, and gene expression analysis was conducted using
Techniques: Expressing, Reverse Transcription, Isolation, Control, Cell Culture, Concentration Assay, DNA Methylation Assay, Activity Assay, In Vitro, Flow Cytometry, Confocal Microscopy, Knock-Out